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KMID : 0816120020050020199
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Korean Journal of Pediatric Gastroenterolology and Nutrition
2002 Volume.5 No. 2 p.199 ~ p.205
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Neonatal Cholestasis Associated with Congenital Hypopituitarism
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Yang Hye-Ran
Song Eun-Kyung
Kim Jeong-Eun
Chung Su-Jin
Lee Kyung-Hun
Shin Choong-Ho
Yang Sei-Won
Ko Jae-Sung
Kang Gyeong-Hoon
Seo Jeong-Kee
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Abstract
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Congenital hypopituitarism is a possible cause of neonatal cholestasis, but the mechanism is still unknown. The pathogenesis of cholestasis may be due to hormone deficiency, which has effects on the physiological maturation of bile acid synthesis and transport. We experienced a case presenting with cholestasis and recurrent hypoglycemia associated with congenital hypopituitarism. Cholestasis resolved with thyroxine and hydrocortisone replacement therapy.
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KEYWORD
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Neonatal cholestasis, Hypopituitarism, Hypoglycemia,
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